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<h1>Methoden in der Pathologie</h1>
<br>

An unserem Zentrum sind direkt oder indirekt alle modernen Methoden der Pathologie 
etabliert. Hierzu geh&ouml;rt die Immunhistologie ebenso wie die 
In-Situ-Hybridisierung und Molekularpathologie.
<br><br>

<img src="images/fotos/60.jpg" width=200 border=1 vspace=10 hspace=15 align=left> 
Hervorzuheben sind vor allem die seit neuerer Zeit etablierten pr&auml;diktiven (prognostischen) 
Marker und therapierelevanten Zielmolek&uuml;le ('targeted therapie') der b&ouml;sartigen Neoplasien. 
Das sind z.B. der EGF-Rezptor bei Adenocarcinomen der Lunge, der Herceptinrezeptor bei 
Mammacarcinomen oder der K-RAS-Genstatus bei Dickdarmcarcinomen (Aufz&auml;hlung ohne Vollst&auml;ndigkeit).
<br><br>

Zur Anwendung kommen neben der Immunhistologie die chromogene In-Situ-Hybridisierung 
(Cish), die PCR-Untersuchung und Gensequenzierung.
Ferner K&ouml;nnen durch diese neueren Methoden famili&auml;r bedingte Krebserkrankungen 
(sog. erblich bedingter Krebs) abgekl&auml;rt werden. 



 
 

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